Cary Grant

Mortimer Brewster

Priscilla Lane

Elaine Harper

Raymond Massey

Jonathan Brewster

Jack Carson

O'Hara

Edward Everett Horton

Mr. Witherspoon

Peter Lorre

Dr. Einstein

James Gleason

Police Lt. Rooney

Josephine Hull

Abby Brewster

Jean Adair

Martha Brewster

John Alexander

'Teddy Roosevelt' Brewster

Grant Mitchell

Reverend Harper

Edward McNamara

Brophy

Garry Owen

Taxi Cab Driver

John Ridgely

Saunders

Vaughan Glaser

Judge Cullman

Chester Clute

Dr. Gilchrist

Charles Lane

Reporter

Edward McWade

Gibbs